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Product and a kind of method of the inhibition for the treatment for being responsible for common allergy for reagin

机译:产品和一种抑制常见原因引起的过敏反应的治疗方法

摘要

This invention pertains to allergen-containing substances, methods of preparing the same and using the same as immunologically specific suppressants of the production of reaginic antibodies directed to the allergen in question. The allergen-containing substances can be characterized as covalent conjugates of the allergen molecules with non-immunogenic water-soluble polymers. The degree of conjugation is such that the conjugates are rendered tolerogenic as well as substantially non-allergenic and non-immunogenic. The new conjugates are useful for immunologically specific suppression of common allergies in mammals, including humans, which are mediated by reaginic antibodies of the IgE class.
机译:本发明涉及含变应原的物质,其制备方法和使用该物质作为产生针对所述变应原的尿素抗体的免疫学特异性抑制剂的方法。含变应原的物质可以表征为变应原分子与非免疫原性水溶性聚合物的共价缀合物。缀合的程度使得缀合物具有致耐受性以及基本上非致敏性和非免疫原性。新的缀合物可用于免疫特异性抑制哺乳动物(包括人)中常见的变态反应,这些变态反应是由IgE类的尿素抗体介导的。

著录项

  • 公开/公告号NO148281C

    专利类型

  • 公开/公告日1983-09-14

    原文格式PDF

  • 申请/专利权人 PHARMACIA AB;

    申请/专利号NO19770002848

  • 发明设计人 LEE WENG YEK;SEHON ALEC;

    申请日1977-08-15

  • 分类号A61K39/35;C07G7/00;

  • 国家 NO

  • 入库时间 2022-08-22 11:05:11

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