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new derivatives of substituted dinoreburnamenine 20, 21 in the intermediate cycle, process and preparation, application as medicine and the containing compositions
new derivatives of substituted dinoreburnamenine 20, 21 in the intermediate cycle, process and preparation, application as medicine and the containing compositions
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机译：中间周期，方法和制备中的取代的地诺布尔南宁20、21的新衍生物，用作药物及所含组合物
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摘要
Novel 20,21-dinoreburnamenines of the formula IMAGE I wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms and =CH2, the wavy line connecting to the E ring being a single bond when R is hydrogen or alkyl of 1 to 4 carbon atoms or a double bond when R is =CH2 and the dotted line being possibly an endo carbon-carbon bond when R is hydrogen or alkyl of 1 to 4 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts in all their possible isomers forms, racemic mixtures and optical isomers having oxygenating and cerebral vasoregulating activity of great value and a novel process and intermediates for their preparation.
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