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INHIBITION OF GASTRIC ACID SECRETION AND INGESTIVE COMPOSITION FOR INHIBITING GASTRIC ACID SECRETION

机译:抑制胃酸分泌和抑制胃酸分泌的成分

摘要

A method for inhibiting the secretion of stomach acid in vertebrate animals. The method comprises contacting the lumen side of the stomach with a compound which interferes with the acid secretion mechanism yet cannot permeate the lining of the stomach. The compound has a molecular weight of less than 1,200 and at least ten percent of the molecular weight of the compound is due to the molecular weight contribution of secondary amine nitrogen. The invention also includes an ingestible product for inhibiting the secretion of stomach acid in vertebrate animals. The product is ingested so that it is contacted with the lumen side of the stomach to interfere with the acid secretion mechanism without permeating the lining of the stomach. The product contains a compound which has a molecular weight of less than 1200, at least ten percent of the molecular weight of the compound being due to the molecular weight contribution of secondary amine nitrogen. The product is in the form of a solution, dispersion, capsule or tablet.
机译:在脊椎动物中抑制胃酸分泌的方法。该方法包括使胃的管腔侧与一种化合物接触,该化合物干扰酸的分泌机制,但不能渗透到胃的壁中。该化合物的分子量小于1200,并且该化合物的分子量的至少百分之十是由于仲胺氮的分子量贡献。本发明还包括用于抑制脊椎动物中胃酸分泌的可摄取产品。摄入产品后,使其与胃的内腔侧接触,以干扰酸的分泌机制,而不会渗透到胃壁。该产物包含分子量小于1200的化合物,该化合物的分子量的至少百分之十是由于仲胺氮的分子量贡献。该产品为溶液,分散液,胶囊或片剂的形式。

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