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N-HYDROXYALCYLEDICED DICARBOXYLIC ACID BIS (3,5-DICARBAMOYL-1-2,4,6-TRYODANANIDES PROCEDURES FOR PREPARING THEREOF AND XENTIC CONTENTS WITH CONTENTS
N-HYDROXYALCYLEDICED DICARBOXYLIC ACID BIS (3,5-DICARBAMOYL-1-2,4,6-TRYODANANIDES PROCEDURES FOR PREPARING THEREOF AND XENTIC CONTENTS WITH CONTENTS
Novel N-hydroxyalkylated dicarboxylic acid bis(3,5-dicarbamoyl-2,4,6-triiodoanilides) have Formula I IMAGE (I) wherein R1 is a lower, linear or branched mono- or polyhydroxyalkyl residue, R2 is hydrogen, lower alkyl, or R1, R3 is lower mono- or dihydroxyalkyl, and X is a direct bond or linear or branched alkylene, which can be interrupted by one or more oxygen atoms or substituted by hydroxy or alkoxy groups. The novel dimeric compounds of Formula I possess good pharmacological and physicochemical properties making them very advantageous as radiopaque agents in all fields of application for water-soluble, iodine-containing X-ray contrast media.
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