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2,2-Disubstd benzodioxoles - having antiinflammatory, analgesic, antitussive, CNS antiarrhythmic, and hypotensive properties
2,2-Disubstd benzodioxoles - having antiinflammatory, analgesic, antitussive, CNS antiarrhythmic, and hypotensive properties
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机译：2,2-二取代的苯并二恶唑-具有抗发炎，镇痛，镇咳，中枢神经系统抗心律不齐和降压特性
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Title cpds. are of formula (I) (where R is H, lower alkyl, lower haloalkyl, lower hydroxyalkyl, or aryl or aralkyl opt. substd. in the aromatic ring by halogen, alkyl, OH or alkoxy, or R may be joined to an alkyl radical in the 2-posn. on the benzodioxole nucleus to form a spiran contg. 4-7C atoms; R1 is H, =1 halogen atom, a lower alkyl, lower haloalkyl, -CH2NR4R5 (where NR4R5 is opt. substd. amino) OH, alkoxy, sulphonic acid, sulphanide, N, N-dialkylsulphamido, NO2, opt. substd. amino or alkylsulphonylamino go. or R1 is a benzene nucleus condensed to the benzodioxole nucleus; R2 is H, alkyl, aryl or OH; m is 0, 1 or 2; R3 is H, lower alkyl, aryl, OH or NO2; n is 0, 1, 2 or 3; X is O or S, Y is H, aryl (opt. substd. in the aromatic ring by halogen, alkyl, OH or alkoxy), X-CH2CH2Y or NR4R5) including their optical isomers, stereoisomers and pharmaceutically acceptable salts. Some of the cpds. also have blood platelet agglutination inhibiting activity.
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