首页> 外国专利> BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR INCLUSION IN LIPOGENESIS INHIBITING COMPOSITIONS

BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR INCLUSION IN LIPOGENESIS INHIBITING COMPOSITIONS

机译:苯并呋喃羧酸衍生物,它们的制备及其在脂肪生成抑制组合物中的应用

摘要

This invetation relates to 2,3-dihydro-2-benzofurancarboxamide derivatives. There are provided 2,3-dihydro-2-benzofurancarboxamide derivatives of formula IMG (I) wherein R is a substituent at the 5-position on the 2,3-dihydrobenzofuran ring system and is a thienyl group, or a phenyl, phenoxy, benzyl or benzoyl group substituted by an alkoxy group of 1 to 6 carbon atoms, a 1-hydroxyethyl group or an acetamido group, or is a substituent at the 4-position on the 2,3-dihydro-benzofuran ring system and is a phenoxy group optionally substituted by alkyl or alkoxy of 1 to 6 carbon atoms, acetamido, 1-hydroxyethyl or nitro. 2,3dihydro-2-benzofurancarboxamide derivatives of formula I have exhibited lipogenesis inhibiting activity and thus find use in animal husbandry to provide a leaner carcass after slaughter.
机译:本发明涉及2,3-二氢-2-苯并呋喃甲酰胺衍生物。提供了式的(I)的2,3-二氢-2-苯并呋喃甲酰胺衍生物,其中R是2,3-二氢苯并呋喃环系的5-位上的取代基并且为噻吩基或苯基。苯氧基,苄基或苯甲酰基被1至6个碳原子的烷氧基,1-羟乙基或乙酰氨基取代,或为2,3-二氢-苯并呋喃环系4位上的取代基,且为任选地被1至6个碳原子的烷基或烷氧基,乙酰氨基,1-羟乙基或硝基取代的苯氧基。式I的2,3二氢-2-苯并呋喃甲酰胺衍生物具有抑制脂肪生成的活性,因此可用于畜牧业以在屠宰后提供更瘦的car体。

著录项

  • 公开/公告号ZA802838B

    专利类型

  • 公开/公告日1981-05-27

    原文格式PDF

  • 申请/专利权人 SHELL RESEARCH LTD;

    申请/专利号ZA19800002838

  • 发明设计人 CARR J;WITIAK D;MERSMANN H;

    申请日1980-05-13

  • 分类号C07D;A61K;

  • 国家 ZA

  • 入库时间 2022-08-22 16:02:45

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