• 主题
高级搜索  >
历史搜索 清空历史
首页> 外国专利> a preparation method for the preparation of anti trombosewerking and / or diagnostic agent for thrombin in blood on the basis of l - shaped argininederivaten, preparationthe formed diagnostic agent and method for preparation of l - argininederivaten.

a preparation method for the preparation of anti trombosewerking and / or diagnostic agent for thrombin in blood on the basis of l - shaped argininederivaten, preparationthe formed diagnostic agent and method for preparation of l - argininederivaten.

机译：一种基于l型精氨酸衍生物的制备抗凝血酶和/或血液中凝血酶的诊断剂的制备方法，所形成的诊断剂和l-精氨酸衍生物的制备方法。

页面导航
  • 摘要
  • 著录项
  • 相似文献

摘要

N2-dansyl-L-arginine esters and amides having the formula IMAGE or the acid addition salts thereof with a pharmaceutically acceptable acid, wherein R is selected from the group consisting of (1) alkoxy, alkenyloxy, alkynyloxy, and cycloalkoxy, respectively, containing not more than 10 carbon atoms, aralkyl of not more than 15 carbon atoms, tetrahydrofurfuryloxy, and alkoxy of not more than 10 carbon atoms substituted with an alkoxy group of not more than 10 carbon atoms, halogen or nitro; (2) IMAGE wherein R1 and R2 are members selected from the group consisting of hydrogen, alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, alkenyl, and alkyl, wherein said member has no more than 10 carbon atoms, and wherein said alkyl may be substituted with a member selected from the group consisting of alkoxy, alkoxycarbonyl, arylcarbamoyl, acyl, acyloxy, N,N-polymethylenecarbamoyl, respectively, containing not more than 10 carbon atoms, and carboxyl; and (2) IMAGE wherein Z is a divalent group containing up to 10 carbon atoms, which consists of more than one group selected from the group consisting of methylene -CH2, monosubstituted methylene IMAGE wherein R3 is selected from the group consisting of alkyl, acyl, alkoxy, and alkoxycarbonyl, respectively, containing not more than 10 carbon atoms, and carbamoyl, and disubstituted methylene IMAGE wherein R4 R5 are alkyl groups of not more than 10 carbon atoms, and which may further contain at least one member selected from the group consisting of oxy-O-, thio -S-, cycloalkylene of not more than 10 carbon atoms, imino IMAGE alkyl substituted imino IMAGE wherein R6 is an alkyl group of not more than 10 carbon atoms, acyl substituted imino IMAGE wherein R7 is an alkyl group of not more than 10 carbon atoms, phenylene IMAGE and carbonyl IMAGE which completes the IMAGE ring together with the said methylene, mono-substituted methylene or disubstituted methylene.
机译：具有式的N 2-丹磺酰基-L-精氨酸酯和酰胺或其与可药用酸的酸加成盐，其中R分别选自（1）烷氧基，烯基氧基，炔基氧基和环烷氧基，含有不超过10个碳原子，不超过15个碳原子的芳烷基，四氢糠基氧基和被不超过10个碳原子的烷氧基，卤素或硝基取代的不超过10个碳原子的烷氧基; （2）<图像>，其中R1和R2是选自氢，烷基，芳基，芳烷基，环烷基，环烷基烷基，烯基和烷基的成员，其中所述成员具有不超过10个碳原子，并且其中所述烷基可以被分别选自碳原子数不超过10的烷氧基，烷氧基羰基，芳基氨基甲酰基，酰基，酰氧基，N，N-聚亚甲基氨基甲酰基和羧基组成的组中的一个取代; （2）。，其中Z为含至多10个碳原子的二价基团，其由多于一个选自以下的基团组成：亚甲基-CH2，单取代的亚甲基，其中R3选自分别包含碳原子数不超过10个的烷基，酰基，烷氧基和烷氧羰基以及氨基甲酰基和二取代的亚甲基，其中R 4 R 5是碳原子数不超过10个，并且还可以至少包含选自氧-O-，硫代-S-，不超过10个碳原子的亚环烷基，亚氨基烷基取代的亚氨基中的一个，其中R6为不超过10个碳原子的烷基，酰基取代的亚氨基，其中R7是不超过10个碳原子的烷基，亚苯基和羰基与所述亚甲基，单取代的亚甲基或二取代基一起完成环ed亚甲基。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号