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Pharmaceutical compound, a process for relieving inflamacao in a body of a live animal, a process to produce an inhibitory effect on the agreagacao platelets from blood.Process to produce an analgesic effect in a body of live animal afflicted by pain and the therapeutic composition
Pharmaceutical compound, a process for relieving inflamacao in a body of a live animal, a process to produce an inhibitory effect on the agreagacao platelets from blood.Process to produce an analgesic effect in a body of live animal afflicted by pain and the therapeutic composition
2-Amino-3-benzoyl-phenylacetamides are provided having the formula: IMAGE wherein: R represent hydrogen or lower alkyl, R1 and R2 represent hydrogen, lower alkyl, cycloalkyl, phenyl and phenyl substituted by lower alkyl, lower alkoxy, halogen, nitro and trifluoromethyl, and R1 and R2 when taken together with the adjacent nitrogen may form a heterocyclic residue; X represents hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; Y represents hydrogen, lower alkyl, lower alkoxy, halogen, trifluoromethyl, lower alkylthio, lower alkyloxythio or lower alkyldioxythio; Am is primary amino (-NH2), methylamino or dimethylamino, and n is 1 to 2 inclusive. The compounds exhibit anti- inflammatory, antipyretic, anti-blood platelet aggregation and analgetic pharmacological activities.
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