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Anticancer agent contg. 5-hydroxy-imidazole deriv. - esp. effective against solid tumours and with no effect on host immunity
Anticancer agent contg. 5-hydroxy-imidazole deriv. - esp. effective against solid tumours and with no effect on host immunity
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机译:抗癌药续。 5-羟基咪唑衍生物。 -尤其是对实体瘤有效,对宿主免疫力无影响
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摘要
Anticancer compsn. contg. 2-methyl-4-carbamoyl-5-hydroxy-imidazole of formula (I) or its salts, is new. (I) is effective against a wide range of cancers, (esp. those of the solid type), and can be given orally. (I) has low toxicity, e.g. acute LD50 in mice is 2 G/kg orally or 130 mg/kg intravenously. The usual dose is 3-10 g/day, esp. as tablets or capsules.
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机译:抗癌药。续式(I)的2-甲基-4-氨基甲酰基-5-羟基-咪唑或其盐是新的。 (I)对多种癌症(尤其是实体型)有效,并且可以口服。 (I)具有低毒性,例如小鼠的急性LD50为口服2 G / kg或静脉内130 mg / kg。通常剂量为3-10克/天,尤其是。作为片剂或胶囊剂。
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