首页> 外国专利> Method of preparation of a vaccine against equine influenza vaccine, 15 and thus obtained.

Method of preparation of a vaccine against equine influenza vaccine, 15 and thus obtained.

机译：由此获得了抗马流感疫苗的疫苗的制备方法15。

页面导航

摘要
著录项
相似文献

摘要

A virulent strain of Equine Rhinopneumonitis (ERP) Virus was passed for 50 passages through the Vero Cell Line (monkey Kidney) at 26 C. At the end of this treatment, it had become attenuated so that a vaccine formed from the virus gave none of the usual ERP symptoms when horses were inoculated with the vaccine by the I. M. route, i.e., they showed none of the usual nasal and ocular discharges, no fever, no anorexia and the like. When the vaccinates were challenged with virulent virus, none of the clinical symptoms of Equine Rhinopneumonitis Virus appeared, while unvaccinated control animals, so challenged, contracted ERP within 3-4 days with all the classical symptoms.PPThe vaccination of a mare prior to breeding and again during her pregnancy will prevent abortions caused by virulent ERP virus. Other horses should be vaccinated once a year in order to prevent the Equine Rhinopneumonitis disease complex. Foals may be vaccinated any time after 1 day of age even in the face of maternal antibody. The ERP Vaccine Virus may be administered parenterally or extra-parenterally to the mucosal surfaces of the body. The I. M. route of inoculation is recommended.

机译：马毒性鼻肺炎病毒（ERP）的强毒株在26 C下通过Vero细胞系（猴子肾脏）传了50代。在该处理结束后，它已被减毒，因此由该病毒形成的疫苗不会产生任何当通过IM途径给马接种疫苗时，通常会出现ERP症状，即它们没有表现出通常的鼻腔和眼部分泌物，没有发烧，没有厌食症等。当疫苗接种强毒病毒后，没有出现马鼻肺炎病毒的临床症状，而未接种对照动物受到了攻击，在3-4天内感染了所有典型症状的ERP。

繁殖前和怀孕期间的母马都可以防止因强毒的ERP病毒引起的流产。其他马匹应每年接种一次疫苗，以预防马鼻肺炎综合症。 1日龄后，即使面对母体抗体，也可以随时接种马驹。 ERP疫苗病毒可以肠胃外或肠胃外施用到身体的粘膜表面。建议使用I. M.接种途径。展开▼

著录项

公开/公告号FR2348704A1

专利类型
公开/公告日1977-11-18

原文格式PDF
申请/专利权人 PHILIPS ROXANE;PHILIPS ROXANE INC;
展开▼

申请/专利号FR19770012208
发明设计人
展开▼

申请日1977-04-22
分类号A61K39/12;C12K5/00;
国家 FR
入库时间 2022-08-22 21:47:30

相似文献

专利
外文文献
中文文献