首页> 外国专利> how przeksztalcania chiralowego acid ester of optically activedrugorzedowym alcohol alpha - cyjanowym configuration (r) in chiralowego acid ester with alcohol drugorzedowym alpha - cyjanowym configuration (s)

how przeksztalcania chiralowego acid ester of optically activedrugorzedowym alcohol alpha - cyjanowym configuration (r) in chiralowego acid ester with alcohol drugorzedowym alpha - cyjanowym configuration (s)

机译:如何将手性酸酯中的光活化仲醇α-氰基构型的手性氨基酸转化为醇仲α-氰基ow构型(s)

摘要

A process for the preparation of an ester of chiral (A) acid with an optically active (S) alpha -cyano-3-phenoxybenzyl alcohol by reacting an ester of chiral (A) acid with alpha -cyano-3-phenoxybenzyl alcohol of the formula IMAGE B in its optically active (R) form or a racemic (R,S) mixture or a mixture of esters of said (R) alcohol and (S) alcohol in non-equimolecular proportions designated herein as "ester (R+S)" with a base selected from the group consisting of ammonium hydroxide, primary, secondary and tertiary amines, quaternary ammonium compounds, liquid amines of high molecular weight, ion exchange resins of a basic character and a catalytic amount of a strong base in at least one solvent in which the ester of the (R) alcohol is soluble and in which the ester of the (S) alcohol is insoluble and recovering from the resulting medium the chiral (A) acid ester of the (S) alcohol which is insoluble.
机译:通过使手性(A)酸的酯与α-氰基-3-苯氧基苄醇的手性(A)的酯与旋光性(S)α-氰基-3-苯氧基苄醇的酯的制备方法以其光学活性(R)形式或所述(R)醇和(S)醇的外消旋(R,S)混合物或酯混合物的非等分子比例的式 B,在本文中称为“酯(R + S)”,其碱选自氢氧化铵,伯,仲和叔胺,季铵化合物,高分子量液体胺,具有碱性的离子交换树脂和催化量的强碱。至少一种溶剂,其中(R)醇的酯是可溶的并且(S)醇的酯是不溶的,并且从所得的介质中回收(S)醇的手性(A)酸酯,其为不溶的。

著录项

  • 公开/公告号PL197553A1

    专利类型

  • 公开/公告日1978-01-02

    原文格式PDF

  • 申请/专利权人 ROUSSEL UCLAF;

    申请/专利号PL19770197553

  • 发明设计人

    申请日1977-04-22

  • 分类号C07C;

  • 国家 PL

  • 入库时间 2022-08-22 22:42:49

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号