首页> 外国专利> PROCESS FOR PRODUCING NEW N-LARGE BRACKET-1-SQUARE BRACKET-BRACKET-1,3-DIHYDRO-1,3-DIOXO-2H-BENZ-SMALL SQUARE BRACKET-D,E-SMALL SQUARE BRACKET CLOSED-ISOQUINOLIN-2-YL-BRACKET CLOSED-ALKYL-SQUARE BRACKET CLOSED-4-PIPERIDINYL-LARGE BRACKET CLOSED-N-PHENYL-ALKANOYL-AMIDES

PROCESS FOR PRODUCING NEW N-LARGE BRACKET-1-SQUARE BRACKET-BRACKET-1,3-DIHYDRO-1,3-DIOXO-2H-BENZ-SMALL SQUARE BRACKET-D,E-SMALL SQUARE BRACKET CLOSED-ISOQUINOLIN-2-YL-BRACKET CLOSED-ALKYL-SQUARE BRACKET CLOSED-4-PIPERIDINYL-LARGE BRACKET CLOSED-N-PHENYL-ALKANOYL-AMIDES

机译：制备新的N型大支架1-方支架--1,3-二氢-1,3-二恶英-2H-本茨-小方支架-D，E-小方支架闭式-异喹啉-2-基-支架封闭的烷基方支架封闭的4-哌啶基大支架封闭的-N-苯基-烷基-酰胺

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摘要

Compounds of the following formula and their acid addition salts WHEREIN R1 and R2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, amino and trifluoromethyl; A is a straight or branched chain alkylene of 1 to 8 carbons; R3 is phenyl or substituted phenyl; and R is lower alkyl or cycloalkyl of 3 to 7 carbons are disclosed. These compounds exhibit antidepressant activity. In addition these compounds are useful as antiinflammatory agents.

机译：在下式的化合物及其酸加成盐中，R 1和R 2独立地选自氢，卤素，低级烷基，低级烷氧基，低级烷硫基，硝基，氰基，氨基和三氟甲基; A为1至8个碳的直链或支链亚烷基; R3是苯基或取代的苯基;公开了R为3至7个碳的低级烷基或环烷基。这些化合物表现出抗抑郁活性。另外，这些化合物可用作抗炎剂。

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公开/公告号HU172542B

专利类型
公开/公告日1978-09-28

原文格式PDF
申请/专利权人 E. R. SQUIBB AND SONSINCUS;
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申请/专利号HU1976SU00909
发明设计人 WADEPETER C.US;VOGTBERTHOLD R.US;
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申请日1976-01-05
分类号C07D401/06;
国家 HU
入库时间 2022-08-22 22:50:32

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