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New derivatives of anthracycline - glycosides, in particular designated under the name of antibiotics, ma 144 - m1 and ma 144 - m2, 1995 of preparation and pharmaceutical compositions containing the said compounds as agents antitumor
New derivatives of anthracycline - glycosides, in particular designated under the name of antibiotics, ma 144 - m1 and ma 144 - m2, 1995 of preparation and pharmaceutical compositions containing the said compounds as agents antitumor
New antitumor agents designated MA 144-M1 and MA 144-M2, which are anthracycline glycosides and inhibit the growth of gram-positive bacteria, e.g. Staphyococcus aureus, Bacillus subtilis and Sarcina lutea, and inhibit the growth of animal tumors such as leukemia L 1210, P 388 and sarcoma 180 are produced by fermentation of MA 144-producing strains of streptomyces and by the chemical or enzymatic conversion of aclacinomycin A or cinerubin A.
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机译：命名为MA 144-M1和MA 144-M2的新抗肿瘤药是蒽环类糖苷，可抑制革兰氏阳性细菌的生长。通过发酵产MA 144的链霉菌菌株并通过化学或酶促转化阿克拉霉素A或cinerubin A.
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