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process for the production of n - (2 - amino - 3,5 - dibrombenzyliden) - trans-4 - aminocyclohexanol and source material for the production of n - (trans-4 - hydroxycyclohexyl) - (2 - amino - 3,5 - dibrombenzyl) amine
process for the production of n - (2 - amino - 3,5 - dibrombenzyliden) - trans-4 - aminocyclohexanol and source material for the production of n - (trans-4 - hydroxycyclohexyl) - (2 - amino - 3,5 - dibrombenzyl) amine
N-(Trans-4-hydroxycyclohexyl)-2-amino-3,5-dibromobenzylamine (I) and its acid addn. salts are prepd. by reducing N-(2-amino-3,5-dibromobenzylidene)-trans-4-aminocyclohexanol (II), pref. with a complex metal hydride (esp. LiAlH4 or NaBH4), and opt. converting the resulting base into a salt. (II) is pref. prepd. by reacting 2-amino-3,5-dibromobenzaldehyde with trans-4-aminocyclohexanol.
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