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Method and apparatus for studying laboratory animal behavior

机译:研究实验动物行为的方法和装置

摘要

A walled enclosure or cage is provided in which laboratory animals may be maintained for observation and evaluation. The floor of the enclosure is provided by a plurality of conductive bar elements that are spacially separate and extend across the bottom of the enclosure. Spacial separation of the bars insulates one from the other and further, space is provided in the floor to remove animal waste, excess food and the like. An electrical resistor is connected between each two adjacent conductive bars and cooperate with the bars to define a resistor network to which a closely controlled feed current is supplied. An animal makes contact with the conductive bars which lowers resistance of the network and produces a voltage change. The resistor network is a.c. coupled to a differential amplifier, and a comparator which receive pulses from capacitors between the network and the amplifier and prepare same for an interface means for a pulse recording system. The amplified pulse may be shaped, divided or the like as required by the recording system. The method of using the present system involves detection of contact between an animal foot and the conductive grid bars, whereupon contact area determines the resistance of the network and a proportional signal is produced therefrom. The signal is then amplified, manipulated to avoid ambient electrical interference, such as an incidental electrical field from line current at 60 Hertz, and/or shaped, divided or the like to provide input to a particular recording system. Raw data from the recording system can then be correlated to locomotor activity of the laboratory animal.
机译:提供有壁的外壳或笼子,其中可以饲养实验动物以进行观察和评估。外壳的底部由多个导电条元件提供,这些导电条元件在空间上是分开的并且在外壳的底部上延伸。杆的空间分隔使彼此隔离,此外,在地板上提供了空间以去除动物粪便,多余的食物等。电阻器连接在每两个相邻的导电条之间,并且与导电条配合以限定电阻器网络,向该电阻器网络提供严格控制的馈电电流。动物与导电条接触,从而降低网络电阻并产生电压变化。电阻网络为交流电耦合到差分放大器和比较器,比较器从网络和放大器之间的电容器接收脉冲,并为脉冲记录系统的接口装置做准备。放大后的脉冲可以根据记录系统的要求进行整形,分割等。使用本系统的方法包括检测动物脚与导电栅栏之间的接触,于是接触面积确定了网络的电阻,并由此产生了比例信号。然后,信号被放大,操纵以避免周围的电干扰,例如来自60赫兹线电流的偶然电场,和/或被整形,分开等以提供输入到特定的记录系统。然后可以将来自记录系统的原始数据与实验动物的运动活动相关联。

著录项

  • 公开/公告号US3974798A

    专利类型

  • 公开/公告日1976-08-17

    原文格式PDF

  • 申请/专利权人 MEETZE JR.;MURRAY O.;

    申请/专利号US19750569599

  • 发明设计人 MURRAY O. MEETZE JR.;

    申请日1975-04-21

  • 分类号A01K29/00;

  • 国家 US

  • 入库时间 2022-08-23 01:30:07

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