首页> 外国专利> METHOD FOR PREPARING A DERIVATIVE 6a-METHYL-19-NORPROGESTERONE The invention relates to a method for producing a new compound, a bos-methyl-19-norprogesterone derivative, with high physiological activity. A known method for producing unsaturated steroid compounds by detating in an acidic environment for preparing the 6a-methyl-19-norprogesterone derivative of a formula which consists in the fact that the compound of the general formula 10

METHOD FOR PREPARING A DERIVATIVE 6a-METHYL-19-NORPROGESTERONE The invention relates to a method for producing a new compound, a bos-methyl-19-norprogesterone derivative, with high physiological activity. A known method for producing unsaturated steroid compounds by detating in an acidic environment for preparing the 6a-methyl-19-norprogesterone derivative of a formula which consists in the fact that the compound of the general formula 10

机译:制备衍生的6a-甲基-19-正孕酮的方法本发明涉及一种具有高生理活性的新化合物bos-甲基-19-正孕酮衍生物的制备方法。一种通过在酸性环境中进行检测来制备不饱和甾族化合物的已知方法,以制备下式的6a-甲基-19-正孕酮衍生物,其在于以下事实:通式10的化合物

摘要

The novel title cpd. may be prepd. by (1) reducing 6-formyl-17 alpha-caproyloxy-20-oxo-19-nor-pregna-3,5-diene with palladium and cyclohexene; (2) reducing a 3,20-dioxo-6-methylene-17 alpha-caproyloxy-19-nor-pregn-4-ene with hydrogen and a palladium catalyst; (3) dehydrating a 3,20-dioxo-5 alpha-hydroxy-6-methyl-17 alpha-caproyloxy-19-nor-pregnane with a base or mineral acid or (4) hydrogenating a 6-disubstd. amino 17 alpha-caproyloxy-20-oxo-19-nor-pregna-3,5-diene with hydrogen and a catalyst.
机译:小说标题cpd。可以准备。通过(1)用钯和环己烯还原6-甲酰基-17α-己酰氧基-20-氧代-19-正戊烯-3,5-二烯; (2)用氢和钯催化剂还原3,20-二氧代-6-亚甲基-17α-己酰氧基-19-nor-pregn-4-烯; (3)用碱或无机酸使3,20-二氧代-5α-羟基-6-甲基-17α-己酰氧基-19-正孕烷脱水或(4)氢化6-二取代。具有氢和催化剂的氨基17α-己酰氧基-20-氧代-19-正戊烯-3,5-二烯。

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