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MSC CELL THIN FILM INTEGRATING GELATIN-FIBROIN COMPOSITE MICROSPHERES, AND PREPARATION METHOD THEREFOR

机译:MSC细胞薄膜整合明胶 - 纤维素复合微球,并制备方法

摘要

Disclosed is a MSC cell thin film integrating gelatin-fibroin composite microspheres, and a preparation method therefor. The MSC cell thin film integrating gelatin-fibroin composite microspheres is obtained by taking gelatin and fibroin protein as high polymer materials, preparing the gelatin-fibroin composite microspheres by means of an emulsion method, performing sterilization on the microspheres, and then inoculating mesenchymal stem cells (MSCs). The microspheres are prepared by combining fibroin protein and gelatin, so that the problem of the fast degradation velocity of gelatin microspheres can be solved. The MSC cell thin film integrating gelatin-fibroin composite microspheres is beneficial for the function extension of the MSC cell thin film, such as realizing combination therapy through loading protein drugs by means of the microspheres, realizing magnetic field manipulation through loading magnetic particles by means of the microspheres, etc. The MSC cell thin film has good application prospects in the field of tissue regeneration.
机译:公开了一种MSC细胞薄膜整合明胶 - 纤维素复合微球,以及其制备方法。通过服用明胶和纤维素蛋白作为高分子材料而获得的MSC细胞薄膜整合,通过乳液方法制备明胶 - 纤维素复合微球,对微球进行灭菌,然后接种间充质干细胞(MSC)。通过组合纤维素蛋白和明胶来制备微球,从而可以解决明胶微球的快速降解速度的问题。将明胶 - 纤维素复合微球的MSC细胞薄膜是有益于MSC细胞薄膜的功能延伸,例如通过微球通过装载蛋白质药物实现联合治疗,通过通过装载磁性颗粒来实现磁场操纵微球等。MSC细胞薄膜在组织再生领域具有良好的应用前景。

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