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Process for THR preparation of natural crystallized thymol from Monarda citriodora (Jammu Monarda) oil

机译:来自 Monarda Citriodora(Jammu Monarda)油的自然结晶胸腺酚的Thr

摘要

The present invention provides an efficient process for the isolation of natural crystallized thymol product derived from crude natural Monarda citriodora (Jammu Monarda) oil useful for incorporation into foods and beverages in amounts due to strong antimicrobial, antibacterial, antioxidant properties as well as for use as a preservative. The recovery of crystallized thymol product obtained is more than 72% from Hexane-Jammu Monarda oil in a ratio 1:1 under specific conditions. A method for preparing natural thymol in crystal form involves providing crude Jammu Monarda oil in a Flask and gradually reducing the temperature of the flask containing Monarda oil:Hexane in a step-wise manner, thereby producing highly pure crystals (≥95.5%) within 48 h. The methods disclosed herein are suitable for pharmaceutical GMP.
机译:本发明提供了用于分离衍生自原子天然的天然结晶静脉醇产物的有效方法,其可用于掺入由于强抗微生物,抗氧化剂,抗氧化剂(抗氧化剂)的量掺入食品和饮料中的用量。抗菌剂(Jammu Monarda)油属性以及用作防腐剂。在特定条件下,在比例1:1的比例1:1中,获得的结晶静脉戊醇产物的回收率从己烷-jammu monarda油中的比例为1:1。一种制备晶体形式的天然胸腺酚的方法涉及在烧瓶中提供粗内蒙纳米油,并逐渐降低含有蒙纳达油的烧瓶温度:己烷以逐步的方式,从而在48内产生高纯晶体(≥95.5%) H。本文公开的方法适用于药物GMP。

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