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METHOD FOR PREPARING BORON SALT OF DIPEPTIDE OF VALINE-PROLINE
METHOD FOR PREPARING BORON SALT OF DIPEPTIDE OF VALINE-PROLINE
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机译：制备缬氨酸二肽二肽的方法
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摘要
Provided is a method for preparing a boron salt of a dipeptide of valine-proline. The method uses pyrrolidine boric acid protected by an R1 group and valine protected by an R4 group as the initial raw materials, and avoids the problem of product loss caused by complex post-processing during deprotection, thereby greatly improving the yield of a target product, and facilitating mass production thereof; and same also uses a resolution method by means of a resolving agent, and avoids the problem of excessive loss of a product with a target configuration caused by using resolution methods with different solubilities, thereby greatly improving the yield of the product with the target configuration.
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