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METHODS AND SYSTEMS FOR THE RAPID DETECTION OF MICROORGANISMS USING RECOMBINANT INFECTIOUS AGENTS TO EXPRESS AN INDICATOR SUBUNIT
METHODS AND SYSTEMS FOR THE RAPID DETECTION OF MICROORGANISMS USING RECOMBINANT INFECTIOUS AGENTS TO EXPRESS AN INDICATOR SUBUNIT
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机译:使用重组传染性药剂快速检测微生物的方法和系统,表达指标亚基
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摘要
Disclosed herein are methods and systems for rapid detection of microorganisms such as bacteria in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene encoding one subunit of an indicator protein. The specificity of the bacteriophage allows detection of a particular bacteria of interest and an indicator signal may be amplified to optimize assay sensitivity.
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