INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES

• 1. 孕激素在制备糖原合成酶激酶-3β抑制剂药物中的应用及糖原合成酶激酶-3β抑制剂 [P] . 中国专利： CN108272804A . 2018-07-13
• 2. 用于抑制催泪成分合成酶基因表达的DNA及其载体、使用该DNA及其载体抑制催泪成分合成酶基因表达的方法以及催泪成分合成酶基因的表达被抑制的植物 [P] . 中国专利： CN1708586A . 2005-12-14
• 3. INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES [P] . 欧洲知识产权局专利： EP3146050B1 . 2020-08-12

  机译： 通过使用反义寡核苷酸产生过早的终止密码子来抑制或下调糖原合成酶

• 4. Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides [P] . 美国专利： US10682423B2 . 2020-06-16

  机译： 通过使用反义寡核苷酸产生过早的终止密码子来抑制或下调糖原合酶

• 5. INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES [P] . 美国专利： US2019117794A1 . 2019-04-25

  机译： 通过使用反义寡核苷酸产生过早的终止密码子来抑制或下调糖原合成酶

• 1. Glycogen synthase kinase-3β inhibitor SB216763 promotes DNA repair in ischemic retinal neurons [J] . Jing Zhang, Zhi-Peng Lai, Pei Chen, 中国神经再生研究（英文版） . 2021,第002期
• 2. Glycogen Synthase Kinase Inhibitor (2'Z,3'E)-6-Bromo-indirubin3'-Oxime Enhances Drug Resistance to 5-FluorouracilChemotherapy in Colon Cancer Cells [J] . Kun-ping Liu, Feng Luo, Si-ming Xie, 中国癌症研究（英文版） . 2012,第002期
• 3. Lithium chloride ameliorates learning and memory ability and inhibits glycogen synthase kinase-3 beta activity in a mouse model of fragile X syndrome [J] . Shengqiang Chen, Xuegang Luo, Quan Yang, 中国神经再生研究（英文版） . 2011,第031期
• 4. Sequence-specific Readthrough of Termination Codon by Antisense Oligonucleotides [C] . Shun Yamashita, Kenichiro Itami, Shinya Hagihara 日本化学会春季年会講演予稿集 . 2018
• 5. Retinal delivery of an aldose reductase inhibitor and a VEGF antisense oligonucleotide. [D] . Aukunuru, Jithan Venkata. 2002
• 6. Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease [O] . Nicholas P Clayton, Carol A Nelson, Timothy Weeden, 2014
• 7. A “combination oligonucleotide” antisense strategy to downregulate thymidylate synthase and decrease tumor cell growth and drug resistance [O] . Randal W Berg, Peter J Ferguson, Mark D Vincent, 2003
• 8. Antisense Oligonucleotides to Glucosylceramide Synthase Can Reverse Multidrug Resistance in Breast Cancer [R] . Liu, Y. 2002

• 1. Corrigendum:Glycogen synthase kinase-3β inhibitor SB216763 promotes DNA repair in ischemic retinal neurons [J] . . 中国神经再生研究：英文版 . 2021,第10期
• 2. The combination of epidermal growth factor and glycogen synthase kinase 3 inhibitor support long-term self-renewal of Sca-1 positive hepatic progenitor cells from normal adult mice [J] . Cai-Xia Jin ,Lisa Samuelson ,Cai-Bin Cui . 干细胞探索（英文） . 2013,第3期
• 3. 杂草对乙酰乳酸合成酶抑制剂产生抗性的机理研究进展 [C] . Xu Xian ,许贤 ,Wang Guiqi . 全国农田杂草抗药性治理技术研讨会 . 2015
• 4. 糖原合成酶激酶-3β抑制剂对大鼠溃疡性结肠炎的抑制作用 [A] . 周倩 . 2014