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ALVELESTAT FOR USE IN THE TREATMENT OF GRAFT REJECTION, BRONCHIOLITIS OBLITERANS SYNDROME AND GRAFT VERSUS HOST DISEASE

机译：Alvelestat用于治疗接枝排斥，支气管炎梗塞综合征和移植物与宿主病

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摘要

The invention relates to treatments for organ rejection, in particular to treatments for lung transplant associated bronchiolitis obliterans syndrome by administering a neutrophil elastase inhibitor, such as alvelestat. The invention also relates to treatments for graft versus host disease.

机译：本发明涉及器官排斥的治疗，特别是通过施用中性粒细胞弹性蛋白酶抑制剂，例如Alvelestat的治疗肺移植相关支气管炎梗阻的治疗。本发明还涉及接枝与宿主病的处理。

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公开/公告号WO2021053058A1

专利类型
公开/公告日2021-03-25

原文格式PDF
申请/专利权人 MEREO BIOPHARMA 4 LIMITED;DUKE UNIVERSITY;NATIONAL CANCER INSTITUTE;
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申请/专利号WO2020EP75948
发明设计人 PARKIN JACQUELINE;SUNG ANTHONY;PAVLETIC STEVEN. Z;IM ANNIE;HOLTZMAN NOA. G;
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申请日2020-09-17
分类号A61K31/444;A61K9;A61K45/06;A61P11;A61P37/06;A61P43;
国家 EP
入库时间 2022-08-24 17:56:57

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