首页> 外国专利> Composition for protecting hepatic damage on heavy metal comprising extracts from Elaeagnus umbellata leaves

Composition for protecting hepatic damage on heavy metal comprising extracts from Elaeagnus umbellata leaves

机译:保护肝脏损伤的肝脏损伤的组合物包含来自Elaeagnus Umbellata叶子的萃取物

摘要

The present invention relates to a composition for protecting liver damage by heavy metals containing a bodhi tree (Elaeagnus umbellata ) leaf extract as an active ingredient, and in detail, to prepare an ethanol extract of bodhi tree leaf, and its toxicity from heavy metals (cadmium or lead) Confirmed relief. According to the present invention, when Cadmium is treated to induce toxicity to HepG2 hepatocytes pre-treated with Bodhi tree leaf extract, cytotoxicity and the amount of cadmium uptake in cells are reduced compared to HepG2 hepatocytes not treated with Bodhi tree leaf extract. It can be used in pharmaceutical compositions and health functional foods useful for preventing and treating liver damage caused by heavy metals by confirming the possibility of mitigating liver damage caused by cadmium of the bodhi tree leaf extract.
机译:本发明涉及一种通过含有菩提树(Elaeagnus Umbellata)叶提取物作为活性成分的重金属保护肝损伤的组合物,并详细地制备菩提树叶的乙醇提取物,其来自重金属(镉或铅)的毒性确认了缓解。根据本发明,当治疗镉以诱导用菩提树叶提取物预处理的HepG2肝细胞诱导毒性,与未处理的Hephi树叶提取物未处理的HepG2肝细胞相比,细胞毒性和细胞中的镉摄取量。它可用于药物组合物和健康功能食品,可用于预防和治疗重金属引起的肝损伤,通过确认由菩提树叶提取物的镉引起的肝脏损伤的可能性。

著录项

  • 公开/公告号KR20210040629A

    专利类型

  • 公开/公告日2021-04-14

    原文格式PDF

  • 申请/专利权人 계명대학교 산학협력단;

    申请/专利号KR1020190123119

  • 发明设计人 양선아;이재열;박세호;

    申请日2019-10-04

  • 分类号A61K36/60;A23L33/105;A61P1/16;A61P39/02;

  • 国家 KR

  • 入库时间 2022-08-24 18:12:26

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