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COMBINATION OF A TYPE II PROTEIN ARGININE METHYLTRANSFERASE INHIBITOR AND AN ICOS BINDING PROTEIN TO TREAT CANCER
COMBINATION OF A TYPE II PROTEIN ARGININE METHYLTRANSFERASE INHIBITOR AND AN ICOS BINDING PROTEIN TO TREAT CANCER
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机译:II型蛋白质精氨酸甲基转移酶抑制剂和ICOS结合蛋白的组合治疗癌症
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摘要
In one aspect, the present invention provides a method of treating cancer in a human in need thereof, the method comprising administering to the human a therapeutically effective amount of a Type II protein arginine methyltransferase (Type II PRMT) inhibitor and administering to the human a therapeutically effective amount of an ICOS binding protein or antigen binding portion thereof. In another aspect, the present invention provides a Type II protein arginine methyltransferase (Type II PRMT) inhibitor and an ICOS binding protein or antigen binding fragment thereof for use in treating cancer in a human in need thereof.
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