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METABOLIC PROFILE SCREENING FOR GESTATIONAL DIABETES

机译:妊娠期糖尿病的代谢型谱筛选

摘要

Described herein are methods, materials, kits, devices, and assays for use in screening, detection, and treatment of diabetes, including diabetes mellitus and gestational diabetes mellitus (GDM). The amount of a plurality of metabolic markers present in a test sample obtained from the subject is measured, followed by comparing the amount of the metabolic markers present in the test sample to reference levels of the markers; and identifying a subject as susceptible to, or as having, diabetes when the amount of each of the measured markers present in the test sample is increased or decreased relative to the reference levels. Also provided is a method of treating diabetes in a subject when the amount of each of the measured markers present in the test sample is increased or decreased relative to the reference levels.
机译:本文描述的是用于筛选,检测和治疗糖尿病的方法,材料,试剂盒,装置和测定,包括糖尿病和妊娠糖尿病(GDM)。测量存在于从受试者获得的测试样品中存在的多种代谢标志物的量,然后比较试验样品中存在的代谢标志物的量与标记的参考水平;当在测试样品中存在的每种测量标记的量增加或减少相对于参考水平时,鉴定受试者或者具有糖尿病的糖尿病。还提供了一种在受试者中治疗糖尿病的方法,当测试样品中存在的每种测量标记的量相对于参考水平增加或降低时。

著录项

  • 公开/公告号WO2021072222A1

    专利类型

  • 公开/公告日2021-04-15

    原文格式PDF

  • 申请/专利权人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;

    申请/专利号WO2020US55020

  • 发明设计人 KOOS BRIAN J.;

    申请日2020-10-09

  • 分类号G01N30/72;G01N33/48;G01N33/50;

  • 国家 US

  • 入库时间 2022-08-24 18:15:58

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