首页> 外国专利> METHOD OF TREATING EPILEPSY OR EPILEPTIC ENCEPHALOPATHY WITH FENFLURAMINE IN PATIENTS WITHOUT PULMONARY HYPERTENSION

METHOD OF TREATING EPILEPSY OR EPILEPTIC ENCEPHALOPATHY WITH FENFLURAMINE IN PATIENTS WITHOUT PULMONARY HYPERTENSION

机译：在没有肺动脉高压的患者中治疗癫痫或癫痫患者癫痫或癫痫患者的方法

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摘要

Provided herein are methods of identifying a patient population as candidates for effective treatment of symptoms of epilepsy or epileptic encephalopathy with fenfluramine or a pharmaceutically acceptable salt thereof, by pre-selecting patients diagnosed with epilepsy or epileptic encephalopathy, assessing the pre-selected patients for being at risk of or exhibiting symptoms of pulmonary hypertension, treating and re-assessing the selected and treated patients for pulmonary hypertension, and identifying treated and re-assessed patients not exhibiting pulmonary hypertension as candidates for effective treatment of epilepsy or epileptic encephalopathy with fenfluramine or a pharmaceutically acceptable salt thereof.

机译：本文提供了通过预选择患有癫痫或癫痫患者的患者，将患者群体鉴定患者患者患者作为患有卵泡或其癫痫患者的癫痫患者或药学上可接受的盐的候选者。有风险或表现出肺动脉高压的症状，治疗和重新评估所选和治疗的肺动脉高压患者，并鉴定治疗和重新评估的患者，而没有表现出肺动脉高压的患者，作为有效治疗癫痫或癫痫患者的癫痫或癫痫脑病的候选者药学上可接受的盐。

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公开/公告号US2021113495A1

专利类型
公开/公告日2021-04-22

原文格式PDF
申请/专利权人 ZOGENIX INTERNATIONAL LIMITED;
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申请/专利号US201917253545
发明设计人 BROOKS M. BOYD;GAIL FARFEL;
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申请日2019-07-03
分类号A61K31/137;A61K31/341;A61K31/585;A61K31/4965;A61K31/343;A61K31/505;A61K31/4985;A61K31/519;A61K31/191;A61K31/20;A61K31/192;A61K9;A61P25/08;A61P9/12;
国家 US
入库时间 2022-08-24 18:20:33

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