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Genome assembly method, genome assembly program and genome assembly apparatus
Genome assembly method, genome assembly program and genome assembly apparatus
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机译:基因组组装方法,基因组组装程序和基因组组装装置
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摘要
Problem to be solved: to reduce the computational load and assemble DNA fragments.Computer for theIn the base sequence of the standard genome which is the genome of the organismFor each of the n-base motifs, which are base sequences containing N bases, the rate of occurrence of each standard is the percentage of appearanceAll of the n-base motifs in the base sequence of DNA fragments based on DNA extracted from biological samples are based on the rate of appearance of the sample, which is the rate of occurrence of each.The discrepancy of the sample appearance rate to each standard appearance rate for all N base motifs is calculated.An n-base motif whose sample appearance rate is above a predetermined valueA number of N base motifs are extracted from the lowest degree of deviationThe nucleotide sequence of DNA fragments is converted into DNA fragments of genome map type using an extracted n-base motif.It is assumed that the DNA fragment of the genome map type is assembled to generate the assembly contig of the DNA of the sample.Diagram
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