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METHODS FOR OBTAINING CYTOTOXIC BENZODIAZEPINE DERIVATIVES
METHODS FOR OBTAINING CYTOTOXIC BENZODIAZEPINE DERIVATIVES
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机译:获得细胞毒性苯二氮卓卓衍生物的方法
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摘要
FIELD: chemistry. ;SUBSTANCE: invention relates to new methods for the preparation of dimeric indolinobenzodiazepine compounds, for example, of the formula 18A and IA and their synthetic precursors.;EFFECT: new and improved processes for the preparation of indolinobenzodiazepine dimers that are more efficient and suitable for large scale manufacturing processes.; ; ;29 cl, 24 ex, 19 dwg
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