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首页> 外国专利> METHOD FOR PREDICTING VASCULAR AGING, METHOD FOR PREDICTING DISEASE RISK, BIOMARKER FOR PREDICTING VASCULAR AGING, BIOMARKER FOR DISEASES, MEASUREMENT KIT, AND DIAGNOSTIC DEVICE

METHOD FOR PREDICTING VASCULAR AGING, METHOD FOR PREDICTING DISEASE RISK, BIOMARKER FOR PREDICTING VASCULAR AGING, BIOMARKER FOR DISEASES, MEASUREMENT KIT, AND DIAGNOSTIC DEVICE

机译：预测血管衰老的方法，预测疾病风险的方法，用于预测血管衰老的生物标志物，生物标志物疾病，测量套件和诊断装置

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Provided are: a biomarker which can be used in the diagnosis of vascular aging in a subject and is included in a biological sample taken from the subject; and a method and a biomarker for not only evaluating the degree of progression of vascular aging in the subject by measuring an expression level of the biomarker but also determining the presence or absence of arteriosclerotic disease, cerebrovascular disease, cardiovascular disease, or other aging-related diseases of the subject. The gene expression level of one or both of CMPK2 and RNF213, which are contained in the biological sample taken from the subject as a biomarker for predicting vascular aging, are measured. In addition, the gene expression level of one or both of CMPK2 and RNF213, which are contained in the biological sample taken from the subject as a biomarker for arteriosclerotic disease, cerebrovascular disease, or cardiovascular disease, are measured. Saliva can be suitably used as a biological sample taken from a subject.
机译：提供：一种生物标志物，可用于诊断受试者中血管老化的诊断，并包含在从受试者中取出的生物样品中;一种方法和生物标志物，不仅通过测量生物标志物的表达水平，而且还测量生物标志物的表达水平，还可以测量动脉粥样硬化疾病，脑血管疾病，心血管疾病或其他衰老相关的存在或不存在的血管衰老的进展程度受试者的疾病。测定了CMPK2和RNF213中的一种或两种的基因表达水平，其包含在从受试者中作为用于预测血管衰老的生物标志物的生物样品中。此外，测量了CMPK2和RNF213中的一种或两种的基因表达水平，其包含在从受试者中作为动脉静脉疾病，脑血管疾病或心血管疾病的生物标志物中获取的生物样品中。唾液可以适合用作从受试者中获取的生物样品。

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