首页> 外国专利> Envenomation therapies and related pharmaceutical compositions, systems and kits

Envenomation therapies and related pharmaceutical compositions, systems and kits

机译：envenomation疗法和相关的药物组合物，系统和套件

页面导航

摘要
著录项
相似文献

摘要

The invention provides methods of treatment, pharmaceutical compositions, systems and kits appropriate for first line and/or adjunct therapy with antivenom using at least one active component, in some instances at least two active components and in other instances no more than two active components selected from the group consisting of a selective secretory PLA₂inhibitor (sPLA2 or PLA₂inhibitor), a metalloproteinase inhibitor, a serine protease inhibitor, antivenom, one or more acetylcholinesterase inhibitors or a nAChR agonist paired with a mAChR antagonist, a NMDA receptor antagonist and a spreading factor inhibitor to treat a subject who suffers from an envenomation, preferably at the time of envenomation and often within a period of less than about an hour after an envenomation or 6 hours after an envenomation and throughout the course of treatment at time with or without antivenom as an adjunct therapy after an envenomation by, for example, a snake or invertebrate.

机译：本发明提供了适合于使用至少一种活性组分的抗静电子适合于第一线和/或辅助治疗的治疗，药物组合物，系统和试剂盒的方法，在某些情况下至少两个活性组分，在其他情况下，不超过两个活性组分由由选择性分泌PLA _{2 抑制剂（SPLA2或PLA _{2 抑制剂）组成的组，金属蛋白酶抑制剂，丝氨酸蛋白酶抑制剂，抗静电子，一种或多种乙酰胆碱酯酶抑制剂或一种NACHR激动剂与MACRAR拮抗剂，NMDA受体拮抗剂和扩散因子抑制剂配对，以治疗患有encenomation的受试者，优选在encenomation的时期，并且经常在encenomation或6后在小于约一小时的时间内。在encenation经过例如蛇或无囚禁后，在envenomation和整个治疗过程中，在整个治疗过程中，随着抗腹膜的疗法耳貂。}}

著录项

公开/公告号US11000506B2

专利类型
公开/公告日2021-05-11

原文格式PDF
申请/专利权人 OPHIREX INC;
展开▼

申请/专利号US201515528418
发明设计人 MATTHEW R. LEWIN;
展开▼

申请日2015-11-20
分类号A61K31/404;A61K31/167;A61K31/445;A61K31/381;A61K31/541;A61K31/405;A61K31/24;A61K31/245;A61K31/16;A61K38/57;A61K9;A61K45/06;A61K39/395;C07K16/18;
国家 US
入库时间 2022-08-24 18:38:19

相似文献

专利
外文文献
中文文献