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GENETICALLY MODIFIED CANNABIS SATIVA PLANTS AND MODIFIED CANNABINOID COMPOUNDS FOR TREATMENT OF SUBSTANCE ADDICTION AND OTHER DISORDERS
GENETICALLY MODIFIED CANNABIS SATIVA PLANTS AND MODIFIED CANNABINOID COMPOUNDS FOR TREATMENT OF SUBSTANCE ADDICTION AND OTHER DISORDERS
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机译：基因改性的大麻苜蓿植物和改性的大麻化合物用于治疗物质成瘾和其他疾病
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摘要
The method of increasing cannabinoid levels in genetically modified cannabis sativa plants is to cause overexpression of the gene that controls the expression of tetrahydrocannabinoleic acid (THCA) synthase and/or cannabidiolic acid (CBDA) synthase. It involves genetically modifying the bis sativa plant. Overexpression of THCA synthase and CBDA synthase is from cannabigerol acid to tetrahydrocannabinoleic acid and cannabidiolic acid, as well as cannabinoids (3aR)-2,4,4-trimethyl-7-pentyl-3,3a,4 ,9b-tetrahydrocyclopenta[c]chromen-9-ol and 2-((1R,5R)-3-methyl-5-(prop-1-en-2-yl)cyclopent-2-ene It catalyzes the increased synthesis of -1-yl)-5-pentylbenzene-1,3-diol. Pharmaceutical compositions comprising modified cannabinoids produced by or synthetically produced by transgenic cannabis sativa plants are used to treat a variety of diseases and conditions.
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