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Use of Eomesodermin to determine risk of allograft rejection

机译:使用eomesodermin来确定同种异体移植抑制的风险

摘要

Pre-existing alloreactive memory T cells are a major barrier to the induction of allograft tolerance in organ transplant recipients. The use of Eomesodermin (Eomes) expression in memory T cells to determine the risk of allograft rejection in a subject is described. Also described is the use of Eomes expression in memory T cells of transplant recipients to modify immunosuppressive therapy.
机译:预先存在的聚核记忆T细胞是对器官移植受体中同种异体移植耐受性的主要屏障。使用eOMesodermin(eomes)表达在存储器T细胞中以确定对象中同种异体移植抑制的风险。还描述了eomes在移植受者的记忆T细胞中表达的用途,以改变免疫抑制治疗。

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