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BIOMARKER COMPOSITION FOR PREDICTING RESPONSE OF CERVICAL CANCER PATIENT TO CHEMORADIOTHERAPY

机译:用于预测宫颈癌患者对化学疗法的生物标志物组合物

摘要

The present invention relates to a biomarker composition for predicting the response of a cervical cancer patient to chemoradiotherapy and, specifically, provides a biomarker composition for predicting the response of a cervical cancer patient to chemoradiotherapy, the composition comprising, as an active ingredient, any one or more RNAs selected from the group consisting of has-miR-150-3p mRNA and PR/SET domain 1 (PRDM1) mRNA. By using the biomarker composition, it is possible to more effectively and easily predict the response of a cervical cancer patient to chemoradiotherapy through a relative change in an RNA expression level. In addition, by providing appropriate treatment for symptoms through the prediction of a response to the therapy, unnecessary treatment is avoided and therapeutic effects can be improved through patient-specific treatment.
机译:本发明涉及一种用于预测宫颈癌患者对化学疗法的响应的生物标志物组合物,具体地提供用于预测宫颈癌患者对化学疗法的响应的生物标志物组合物,该组合物包含作为活性成分的组合物,任何一种或更多选自具有Hase-miR-150-3P mRNA和PR / SET结构域1(PRDM1)mRNA的rNA。通过使用生物标志物组合物,可以更有效地通过RNA表达水平的相对变化更有效地且容易地预测宫颈癌患者对化学疗法的响应。此外,通过预测对治疗的响应来提供适当的治疗症状,避免了不必要的处理,并且可以通过患者特异性治疗来改善治疗效果。

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