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TREATING BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS IN DEMENTIA PATIENTS

机译：治疗痴呆患者的行为和心理症状

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摘要

The present invention provides a method for treating behavioral and psychological symptoms in patient with dementia comprising administering an effective dose of pure 5-HT₆ receptor antagonist, masupirdine or a pharmaceutically acceptable salt thereof either alone or in combination with an acetylcholinesterase inhibitor such as donepezil and NMDA (N-Methyl-D-aspartate) receptor antagonist, memantine. The present invention further provides use of the said compound in the manufacture of a medicament and pharmaceutical compositions comprising the said compounds intended for the treatment of the disorders described herein.

机译：本发明提供了一种治疗患有痴呆患者的行为和心理症状的方法，包括施用有效剂量的纯5-HT <亚> 6 受体拮抗剂，Masupirdine或其药学上可接受的盐或与之结合乙酰胆碱酯酶抑制剂，如多奈哌齐和NMDA（N-甲基-D-天冬氨酸）受体拮抗剂，Memantine。本发明进一步提供了所述化合物在制备药物和药物组合物中的用途，所述药物组合物包含用于治疗本文所述疾病的所述化合物。

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公开/公告号WO2021111330A1

专利类型
公开/公告日2021-06-10

原文格式PDF
申请/专利权人 SUVEN LIFE SCIENCES LIMITED;
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申请/专利号WO2020IB61383
发明设计人 NIROGI RAMAKRISHNA;BHYRAPUNENI GOPINADH;SUBRAMANIAN RAMKUMAR;RAVULA JYOTHSNA;JASTI VENKATESWARLU;SHINDE ANIL KARBHARI;JAYARAJAN PRADEEP;JETTA SATISH;PALACHARLA RAGHAVA CHOWDARY;PANDEY SANTOSH KUMAR;MOHAMMED ABDUL RASHEED;BENADE VIJAY SIDRAM;GOYAL VINOD KUMAR;
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申请日2020-12-02
分类号A61K31/496;A61K31/445;A61K31/13;A61K45/06;A61P25/28;A61P43;A61K9;
国家 IB
入库时间 2022-08-24 19:17:41

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