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MODULATION OF UBIQUITIN CARBOXY-TERMINAL HYDROLASE LIGASE 1 EXPRESSION
MODULATION OF UBIQUITIN CARBOXY-TERMINAL HYDROLASE LIGASE 1 EXPRESSION
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机译:泛素羧酸末端水解酶连接酶1表达的调节
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摘要
Disclosed are compositions and methods for treating neurological diseases, disorders, and injuries in a subject in need thereof. Particularly disclosed are compositions and methods for treating neurological diseases, disorders, and injuries that are associated with upper motor neurons in a subject in need thereof in which methods expression of ubiquitin carboxyl hydrolase ligase 1 (UCHL1) is modulated in the subject, for example, via gene therapy being administered to the subject in order to express UCHL1 in upper motor neurons of the subject.
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