首页> 外国专利> BIOMARKERS FOR PREDICTING PRETERM BIRTH DUE TO PRETERM PREMATURE RUPTURE OF MEMBRANES (PPROM) VERSUS IDIOPATHIC SPONTANEOUS LABOR (PTL)

BIOMARKERS FOR PREDICTING PRETERM BIRTH DUE TO PRETERM PREMATURE RUPTURE OF MEMBRANES (PPROM) VERSUS IDIOPATHIC SPONTANEOUS LABOR (PTL)

机译:用于预测早产引起的早产的生物标志物由于早产的膜(PPROM)与特发性自发劳动(PTL)

摘要

The present invention provides compositions and methods for predicting the probability of preterm birth in a pregnant female. The present invention provides a composition comprising one or more biomarkers selected from the group consisting of the biomarkers set forth in FIGS. 1 and 2 and Tables 1 through 3, 6 through 38, and 44 through 68. In one embodiment, the invention provides a method of determining probability for preterm birth in a pregnant female, optionally preterm birth associated with preterm premature rupture of membranes (PPROM) or preterm birth associated idiopathic spontaneous labor (PTL), the method comprising measuring in a biological sample obtained from the pregnant female one or biomarkers selected from one or more of the biomarkers set forth in FIGS. 1 and 2 and Tables 1 through 3, 6 through 38, and 44 through 68 to determine the probability for preterm birth in said pregnant female.
机译:本发明提供了用于预测怀孕女性早产的概率的组合物和方法。本发明提供了一种组合物,其包含一种或多种选自图1和2中所述的生物标志物的生物标志物。 1 和表1至3,6至38和44至68.在一个实施方案中,本发明提供了一种确定怀孕中早产的概率的方法女性,可选的早产与预早移的膜(PPROM)或早产相关特发作业自发性劳动(PTL)的出生,该方法包括测量从选自一种或多种生物标记物中的妊娠雌性的一种或生物标志物的生物样品中测量在图1和2中阐述。 1 和 2 和表1至3,6至38,和44到68,以确定所述怀孕女性的早产的概率。

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