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BIOMATERIALS FOR BONE TISSUE ENGINEERING

机译：骨组织工程生物材料

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摘要

Provided herein are scaffold biomaterials including a decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularized plant or fungal tissue having a 3-dimensional porous structure; wherein the decellularized plant or fungal tissue may optionally be at least partially coated or mineralized, wherein the scaffold biomaterial may optionally further include a protein-based hydrogel and/or a polysaccharide-based hydrogel, or both. Also provided herein are methods and uses of such scaffold biomaterials, including methods of manufacture as well as methods and uses for bone tissue engineering, for example.

机译：本文提供了支架生物材料，其包括除去细胞材料和组织的细胞材料和核酸的真菌组织，脱细胞植物或具有三维多孔结构的真菌组织;其中脱细胞植物或真菌组织可任选地至少部分涂覆或矿化，其中支架生物材料可任选地还包括蛋白质的水凝胶和/或基于多糖的水凝胶，或两者。本文还提供了这种支架生物材料的方法和用途，包括制造方法以及例如骨组织工程的方法和用途。

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公开/公告号WO2021119830A1

专利类型
公开/公告日2021-06-24

原文格式PDF
申请/专利权人 SPIDERWORT INC.;UNIVERSITY OF OTTAWA;
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申请/专利号WO2020CA51750
发明设计人 LEBLANC LATOUR MAXIME;HICKEY RYAN;CUERRIER CHARLES M.;PELLING ANDREW E.;TARAR MARYAM;CATELAS ISABELLE;
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申请日2020-12-18
分类号A61L27/52;A61F2/28;A61F2/30;
国家 CA
入库时间 2022-08-24 19:37:51

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