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首页> 外国专利> DYNAMIC ANTIRETROVIRAL HIV-INFECTION THERAPY

DYNAMIC ANTIRETROVIRAL HIV-INFECTION THERAPY

机译：动态抗逆转录病毒HIV感染治疗

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FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to a method of treating HIV infection. The method consists in the fact that when HIV infection is detected in a patient treatment is started by administering three antiretroviral drugs, namely a non-nucleoside reverse transcriptase inhibitor or a protease inhibitor, or an integrase inhibitor such as dolutegravir, in combination with two nucleoside reverse transcriptase inhibitors, one of which is tenofovir, for at least 6 months, and then after the level of HIV RNA in the blood reaches less than 50 copies/ml and the level of CD4 T-lymphocytes is at least 450 cells/mcl in at least two measurements at an interval of 1 month, lifelong administering of dolutegravir at a dosage of 50 mg and emtricitabine at a dosage of 200 mg is started. ;EFFECT: proposed method can be used for effective treatment of patients with HIV infection in order to minimize risks of developing adverse events in conducted therapy.;4 cl, 1 dwg, 3 ex
机译：现场：药物。物质：发明涉及药物，即治疗HIV感染的方法。该方法包括：当在患者治疗中检测到HIV感染时，通过施用三种抗逆转录病毒药物，即非核苷逆转录酶抑制剂或蛋白酶抑制剂，或蛋白酶抑制剂如DoluteGravir，与两个核苷组合开始逆转录酶抑制剂，其中一个是替诺福韦，至少6个月，然后在血液中的HIV RNA水平达到小于50份/ ml并且CD4 T淋巴细胞的水平至少为450个细胞/ MCL在1个月的间隔下至少两次测量，开始在50mg的剂量和200mg的剂量的剂量下终身施用DoluteGravir。 ;效果：提出的方法可用于有效治疗艾滋病毒感染患者，以最大限度地减少在进行治疗中发育不良事件的风险。; 4 cl，1 dwg，3前

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