首页> 外国专利> TREATMENT OF MEMBRANOUS NEPHROPATHY, IGG4-RELATED DISEASE, AND ANTIPHOSPHOLIPID SYNDROME USING BTK INHIBITOR 2-(3R)-3-4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO3,4-dPYRIMIDIN-1-YLPIPERIDINE-1-CARBONYL-4-METHYL-4-4-(OXETAN-3-YL)PIPERAZIN-1-YLPENT-2-ENENITRILE

TREATMENT OF MEMBRANOUS NEPHROPATHY, IGG4-RELATED DISEASE, AND ANTIPHOSPHOLIPID SYNDROME USING BTK INHIBITOR 2-(3R)-3-4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO3,4-dPYRIMIDIN-1-YLPIPERIDINE-1-CARBONYL-4-METHYL-4-4-(OXETAN-3-YL)PIPERAZIN-1-YLPENT-2-ENENITRILE

机译：使用BTK抑制剂2 - [（3R）-3- [4-氨基-3-（2-氟-4-苯氧基 - 苯基）吡唑[3,4-D ]吡啶胺-1-基]哌啶-1-羰基] -4-甲基-4- [4-（Oxetan-3-Y1）哌嗪-1-基] PET-2-烯腈

页面导航

摘要
著录项
相似文献

摘要

The present disclosure provides methods of treating a disease chosen from membranous nephropathy (MN), IgG4-related diseases, and antiphospholipid syndrome (APS) in a mammal using, e.g., a therapeutically effective amount of, the BTK inhibitor 2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile or a pharmaceutically acceptable salt thereof.

机译：本公开提供了治疗哺乳动物中选择的膜肾病（Mn），IgG4相关疾病和抗磷脂综合征（APS）的治疗疾病的方法，例如。，治疗有效量BTK抑制剂2 - [（3R）-3- [4-氨基-3-（2-氟-4-苯氧基 - 苯基）吡唑[3,4-D]嘧啶-1-基]哌啶-1-羰基] - 4-甲基-4- [4-（OXETAN-3-基）哌嗪-1-基] PET-2-烯腈或其药学上可接受的盐。

著录项

公开/公告号WO2021141919A1

专利类型
公开/公告日2021-07-15

原文格式PDF
申请/专利权人 PRINCIPIA BIOPHARMA INC.;
展开▼

申请/专利号WO2021US12211
发明设计人 NUNN PHILIP;LANGRISH CLAIRE;THOMAS DOLCA;
展开▼

申请日2021-01-05
分类号A61K31/519;A61P37/06;A61K45/06;
国家 US
入库时间 2022-08-24 19:58:07

相似文献

专利
中文文献