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Microparticles for bioanalytical investigations and methods for producing such a microparticle
Microparticles for bioanalytical investigations and methods for producing such a microparticle
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机译：用于生物分析研究的微粒和制备这种微粒的方法
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摘要
The invention relates to a microparticle for bioanalytical investigations and a method for its production. The microparticle is suitable for being transported in a fluid stream through a flow cell of a flow cytometer. The microparticle has a solid particle core and at least one nucleic acid sense biomolecule that is binding-specific for an antisense biomolecule. A layer of a water-soluble conjugate is arranged on the particle core, which comprises at least one linear polymer and / or copolymer which a) has at least one first group by means of which the polymer and / or copolymer can be crosslinked by irradiation with optical radiation of a discrete wavelength, b) has at least one second group to which the at least one nucleic acid sense biomolecule is conjugated, andc) has at least one third group which is bonded to the surface of the particle core via a functional linker group, the linker group for Binding to the at least one nucleic acid sense biomolecule is incapable.
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