首页> 外国专利> COMPOSITION FOR ALLEVIATING PULMONARY HYPERTENSION, METHOD FOR PREDICTING PROGNOSIS OF PULMONARY HYPERTENSION, METHOD FOR ASSISTING IN DETERMINING SEVERITY OF PULMONARY HYPERTENSION, AND METHOD FOR ASSISTING IN DIAGNOSING PULMONARY HYPERTENSION

COMPOSITION FOR ALLEVIATING PULMONARY HYPERTENSION, METHOD FOR PREDICTING PROGNOSIS OF PULMONARY HYPERTENSION, METHOD FOR ASSISTING IN DETERMINING SEVERITY OF PULMONARY HYPERTENSION, AND METHOD FOR ASSISTING IN DIAGNOSING PULMONARY HYPERTENSION

机译：用于缓解肺动脉高压的组合物，预测肺动脉高压预后的方法，辅助确定肺动脉高压的严重程度，以及辅助诊断肺动脉高压的方法

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摘要

The present invention provides: (1) a composition which is for alleviating pulmonary hypertension and contains, as an active ingredient, at least one substance that normalizes the intestinal flora of patients with pulmonary hypertension; (2) a method for predicting the prognosis of patients with pulmonary hypertension or for assisting in determining the severity of pulmonary hypertension, the method comprising a step for detecting at least one kind of bacteria selected from among bacteria belonging to the genus Micrococcaceae, bacteria belonging to the genus Streptococcaceae, bacteria belonging to the genus Pasteurellaceae, bacteria belonging to the genus Veillonellaceae, and bacteria belonging to the genus Lactobacillaceae, in the intestinal flora of the patients with pulmonary hypertension; and (3) a method for assisting in diagnosing pulmonary hypertension, the method comprising comparing the IgA concentration in the feces of a subject with that of a healthy subject.

机译：本发明提供：（1）一种用于减轻肺动脉高压并含有活性成分的组合物，其至少一种物质使肺动脉高压患者肠道菌群正常化; （2）一种方法，用于预测肺动脉高压患者预后或辅助确定肺动脉高压的严重程度的方法，该方法包括检测从属于细菌属于细菌的细菌中选择的至少一种细菌的步骤对于肺炎群患者患者肺动脉高压患者的患者肠道菌群中，属于Pasteurellaceae的细菌，属于Pasteurellaceae的细菌，属于Veillonellaceae属的细菌，以及属于乳杆菌属的细菌; （3）一种辅助诊断肺动脉高压的方法，该方法包括将受试者的粪便中的IgA浓度与健康受试者进行比较。

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公开/公告号WO2021167088A1

专利类型
公开/公告日2021-08-26

原文格式PDF
申请/专利权人 NAKAOKA YOSHIKAZU;ASANO RYOTARO;OGO TAKESHI;JSR CORPORATION;
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申请/专利号WO2021JP06448
发明设计人 NAKAOKA YOSHIKAZU;ASANO RYOTARO;OGO TAKESHI;
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申请日2021-02-19
分类号A61K45;A61P9/12;A61P11;A61P31/04;A61P43;C12N7;C12N1/20;C12Q1/04;A61K38/08;C12N9/99;G01N33/50;G01N33/68;A61K31/4164;A61K31/43;A61K31/7036;
国家 JP
入库时间 2022-08-24 20:50:03

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