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ARGININE DEIMINASE, INCLUDED IN ERYTHROCYTES AND THEIR APPLICATION IN THE TREATMENT OF CANCER AND ARGINASE-1 INSUFFICIENCY
ARGININE DEIMINASE, INCLUDED IN ERYTHROCYTES AND THEIR APPLICATION IN THE TREATMENT OF CANCER AND ARGINASE-1 INSUFFICIENCY
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机译:精氨酸脱氨酶,包括在红细胞中及其在治疗癌症和氨基酶-1不足的应用中的应用
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摘要
The present invention is related to arginine deiminase encapsulated into erythrocytes for use in therapy. It is in particular related to the use thereof in treating arginase-1 deficiency. Also, it relates to novel pharmaceutical compositions comprising arginine deiminase from M. arginini encapsulated into erythrocytes and the use thereof in treating diseases that may beneficiate from arginine depletion, such as arginine dependent cancers, in particular arginine-auxotrophic cancers, and arginase-1 deficiency.
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