首页> 外国专利> REAGENT KIT FOR MEASURING GLYCATED ALBUMIN RATIO AND METHOD FOR MEASURING GLYCATED ALBUMIN RATIO BY USING SAME

REAGENT KIT FOR MEASURING GLYCATED ALBUMIN RATIO AND METHOD FOR MEASURING GLYCATED ALBUMIN RATIO BY USING SAME

机译:用于测量糖化白蛋白比的试剂盒及其通过使用相同测量糖化白蛋白比例的方法

摘要

The present invention relates to a reagent kit for measuring a glycated albumin ratio and a method for measuring a glycated albumin ratio by using same, whereby diagnosis can be made of the presence or absence of diabetes mellitus. More specifically, the present invention relates to a reagent kit for measuring a glycated albumin ratio, comprising an albumin antibody-conjugated gold nanoparticle and a dye-conjugated boronic acid derivative, and a method for measuring a glycated albumin ratio by using same. The reagent kit for measuring a glycated albumin ratio of the present invention comprises: (a) an albumin detection particle conjugated with an albumin antibody binding specifically to albumin; and (b) a boronic derivative conjugated with a dye for specifically detecting glycated albumin. The reagent kit for measuring a glycated albumin ratio according to the present invention comprises "an albumin-detecting particle conjugated with an albumin antibody binding specifically to whole albumin" and "a boronic acid derivative conjugated with a dye for binding specifically to glycated albumin" and as such, can individually measure levels of samples by detecting signals of respective dyes for the samples, without interfering with the intrinsic absorption wavelength of each dye, whereby blood glycated albumin ratios can be easily calculated.
机译:本发明涉及用于测量糖化白蛋白的试剂盒,其通过使用该试剂试剂盒和用于测量糖化白蛋白比的方法,从而可以诊断糖尿病的存在或不存在。更具体地,本发明涉及用于测量糖化白蛋白比的试剂盒,其包含白蛋白抗体 - 缀合的金纳米粒子和染料缀合的硼酸衍生物,以及通过使用该方法测量糖化白蛋白比的方法。用于测量本发明的糖化白蛋白比的试剂盒包括:(a)与特异性与白蛋白特异性结合的白蛋白抗体结合的白蛋白检测粒子; (b)与染料缀合的硼隆衍生物,用于特异性地检测糖化白蛋白。用于测量根据本发明的糖化白蛋白的试剂盒包含“与特异性结合的白蛋白抗体与全白蛋白结合的白蛋白检测颗粒”和“与染料结合的硼酸衍生物特异性与糖化白蛋白结合”和因此,可以通过检测样品的各种染料的信号来单独测量样品的水平,而不会干扰每种染料的内在吸收波长,从而可以容易地计算血液糖化白蛋白比率。

著录项

  • 公开/公告号WO2021177560A1

    专利类型

  • 公开/公告日2021-09-10

    原文格式PDF

  • 申请/专利权人 DXGEN CORP.;

    申请/专利号WO2020KR18295

  • 发明设计人 LEE JIN WOO;CHEON SEON AH;YOO MIN SANG;

    申请日2020-12-15

  • 分类号G01N33/68;G01N33/543;G01N33/558;G01N21/84;G01N21/75;G01N21/77;

  • 国家 KR

  • 入库时间 2022-08-24 20:58:52

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