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Method for determining optical properties in scattering target regions such as optical tissue.
Method for determining optical properties in scattering target regions such as optical tissue.
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机译：用于确定散射目标区域的光学性质，例如光学组织。
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摘要
The method according to the invention for determining optical properties in scattering target regions, such as biological tissue, is used in the medical field, for example in near-infrared spectroscopy (NIRS) of the brain: using transmitting optodes, infrared radiation is generated on the skin surface of the head. Radiation of different wavelengths is irradiated and the backscattered radiation is measured at receiver optodes in order to allow conclusions to be drawn about the oxygen supply to the brain surface. Previous problems with such methods relate, among other things, to the susceptibility to interference from movements of the optodes, device-related signal drifts, difficulties in discriminating the measurement depth (superficial skin layers, deeper brain layers) and difficulties in obtaining comparable (absolute) measured values at different measuring points on the head and at different times . The invention solves such problems without making assumptions about the expected course of time by a calculation model separating the device parameters and the movement-sensitive optode-tissue transitions from the tissue layers. For this purpose, optodes are arranged in such a way that technical factors, on the one hand, and tissue parameters to be measured, on the other hand, each influence a number of redundant measurement channels in weighting. In this way, inverse solutions for the desired tissue data can be separated from artifacts, influencing different weighting. In this way, inverse solutions for the desired tissue data can be separated from artifacts. An optode arrangement and a computing unit for performing the calculations are proposed as devices for use in the method.
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