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MINI-NUCLEOSOME CORE PROTEINS AND USE IN NUCLEIC ACID DELIVERY
MINI-NUCLEOSOME CORE PROTEINS AND USE IN NUCLEIC ACID DELIVERY
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机译:迷你核小核心核蛋白和在核酸输送中使用
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摘要
The present disclosure provides compositions and methods relating to mini-nucleosome core proteins and/or delivery of nucleic acids. In particular, the present disclosure includes, among other things, non-viral proteinaceous vehicles for delivery of nucleic acids. In various embodiments, non-viral proteinaceous vehicles provided herein include (a) a nucleic acid binding domain; (b) a targeting domain; and, optionally, (c) a nucleic acid release domain, stability domain, and/or an oligomerization domain, and/or a linker domain.
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