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PROGNOSTIC PATHWAYS FOR HIGH RISK SEPSIS PATIENTS
PROGNOSTIC PATHWAYS FOR HIGH RISK SEPSIS PATIENTS
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机译：高风险脓毒症患者的预后途径
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摘要
The present invention relates to means and methods that can determine the functional status of a blood sample of a subject having sepsis, a subject suspected to have sepsis or a subject at risk to develop sepsis. The functional status of the blood sample can be used for diagnosing the subject to have sepsis, or can be used for making a prediction, e.g. whether the subject is likely to develop sepsis, or whether the subject has a high mortality risk as a result of sepsis. The functional status of the blood sample is based on the AR signaling pathway activity, optionally combined with the TGFbeta, MAPK-AP1 and/or JAK-STAT3 signaling pathway activities.
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