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首页> 外国专利> COMPOSITION FOR PREVENTING OR TREATING INFLAMMATION, ALLERGIES AND ASTHMA, CONTAINING VERONICASTRUM SIBIRICUM L. PENNELL AS ACTIVE INGREDIENT, AND USE THEREOF

COMPOSITION FOR PREVENTING OR TREATING INFLAMMATION, ALLERGIES AND ASTHMA, CONTAINING VERONICASTRUM SIBIRICUM L. PENNELL AS ACTIVE INGREDIENT, AND USE THEREOF

机译：用于预防或治疗炎症，过敏性和哮喘的组合物，含有Veronicastrum sibiricum L.Pennell作为活性成分，以及其用途

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摘要

The present disclosure relates to a composition including a Veronicastrum sibiricum L. Pennell extract (genus Veronicastrum) for prevention or treatment of inflammation, allergies, and asthma The Veronicastrum sibiricum L. Pennell extract (genus Veronicastrum) is useful as a pharmaceutical composition, health functional food, or health supplement food for prevention and treatment of inflammation, allergies, and asthma due to the confirmation, through various animal experiments, that a Veronicastrum sibiricum L. Pennell (genus Veronicastrum) extract exhibits excellent anti-inflammatory, anti-allergic and asthma-inhibitory activity, the animal experiments including: evaluation of inhibition of leukotriene production (Experimental Example 1); effects on the total number of cells in bronchoalveolar lavage (BAL) fluid by using male Balb/c mice (Experimental Example 2); effects on the number of neutrophil cells relative to the total number of cells in the BAL fluid (Experimental Example 3); effects on the number of Neutrophil+/Gr-1+ absolute cells in the BAL fluid (Experimental Example 4); effects on the number of CD11b+/Gr-1+ absolute cells from among lung cells (Experimental Example 5); effects on the number of CD4+/CD3+ absolute cells from among lung cells (Experimental Example 6); effects on the number of Macrophage+/CD11b+ absolute cells from among lung cells (Experimental Example 7); effects on the expression of inflammation factors in the BAL fluid (Experimental Example 8); and the like.
机译：本公开涉及一种组合物，其包括veronicastrum sibiricum l.Pennell提取物（Genus Veronicastrum）用于预防或治疗炎症，过敏和哮喘，Veronicastrum sibiricum L.Pennell提取物（Genus Veronicastrum）可用作药物组合物，健康功能用于预防和治疗炎症，过敏和哮喘的食品，或健康补充食品由于确认，通过各种动物实验，veronicastrum sibiricum l.Pennell（Genus Veronicastrum）提取物具有优异的抗炎，抗过敏和哮喘 - 抑制动物实验，包括：对白三烯生产的抑制评估（实验例1）;使用雄性BALB / C小鼠对支气管肺泡灌洗（BAL）流体细胞总数的影响（实验例2）;对嗜中性粒细胞数量相对于BAL流体中细胞总数的影响（实验例3）;对BAL流体中的嗜中性粒细胞+ / GR-1 +绝对细胞数的影响（实验例4）;对肺细胞中CD11b + / gr-1 +绝对细胞数量的影响（实验例5）;对肺细胞中CD4 + / CD3 +绝对细胞数的影响（实验例6）;对肺细胞中巨噬细胞+ / CD11b +绝对细胞数的影响（实验例7）;对BAL流体炎症因子表达的影响（实验例8）;等等。

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