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MICROBIOME FINGERPRINTS, DIETARY FINGERPRINTS, AND MICROBIOME ANCESTRY, AND METHODS OF THEIR USE
MICROBIOME FINGERPRINTS, DIETARY FINGERPRINTS, AND MICROBIOME ANCESTRY, AND METHODS OF THEIR USE
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机译：微生物胺指纹，膳食指纹和微生物组血统，以及它们使用的方法
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摘要
A deep metagenomic sequencing of more than 1000 individual gut microbiomes, coupled with detailed long-term diet, fasting, and same-meal postprandial cardiometabolic blood markers analyses, is described. Strong associations between a set of microbes and specific nutrients, foods, food groups, and general dietary indices are demonstrated. Microbial biomarkers of obesity were reproducible across cohorts, but blood markers of cardiovascular disease and impaired glucose tolerance were more strongly associated with microbiome structures. Panels of intestinal microbial species associated with different conditions and/or habits are identified, enabling stratification of the gut microbiome into generalizable health levels among individuals even without clinically manifest disease.
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