首页>
外国专利>
Methods of sensitizing estrogen receptor positive (ER+) breast cancer cells to endocrine therapy
Methods of sensitizing estrogen receptor positive (ER+) breast cancer cells to endocrine therapy
展开▼
机译：将雌激素受体阳性（ER +）乳腺癌细胞敏感到内分泌治疗的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
Aspects of the technology are directed to a method of increasing sensitivity of estrogen receptor positive (ER+) breast cancer cells to treatment with an endocrine therapy. The method involves selecting ER+ breast cancer cells, and administering to the selected cells (i) one or more mammalian target of rapamycin (mTOR) inhibitors and (ii) one or more MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1) inhibitors in an effective amount to increase the sensitivity of the ER+ breast cancer cells to treatment with the endocrine therapy. Methods of treating a subject having ER+ breast cancer are also disclosed.
展开▼
