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A method for detecting genome-related information of cells coexisting with one or more test substances

机译:一种检测与一种或多种测试物质共存的细胞基因组相关信息的方法

摘要

The present invention provides a method for detecting genome-related information of cells coexisting with one or more test substances for various test substances. More specifically, the present invention is a method for detecting genome-related information of a cell or its origin coexisting with one or more kinds of test substances, and one or more kinds of test substances and a first bar code nucleic acid. Prepare multiple first compartments containing, and a second compartment containing cells or their derivatives and second barcode nucleic acid ligation beads; one first compartment and one second compartment. A plurality of third compartments were created by fusing the above; the genome-related nucleic acid and the first barcode nucleic acid were each hybridized with the second barcode nucleic acid to obtain a hybridized complex; Providing a method comprising producing a derived amplification; detecting genome-related information after coexistence of the test substance in a cell using the expression pattern of the amplification as an index.
机译:本发明提供了一种用于检测与各种测试物质的一个或多个测试物质共存的细胞基因组相关信息的方法。更具体地,本发明是一种检测细胞或其原点与一种或多种测试物质共存的基因组相关信息的方法,以及一种或多种测试物质和第一条码核酸。制备含有的多个第一隔室,以及含有细胞或其衍生物和第二条形码核酸结扎珠子的第二隔室;一个第一隔间和一秒钟的隔间。通过熔合上述内容产生多个第三隔室;将基因组相关的核酸和第一条形码核酸各自与第二条形码核酸杂交,得到杂交的复合物;提供一种方法,包括产生衍生扩增;使用扩增的表达模式作为指数在电池中的测试物质共存之后检测基因组相关信息。

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